MCM5 technology

Our tests use a patented technology to detect a protein produced by the expression of the MCM5 (Minichromosome Maintenance Complex Component 5) gene in urine, which can rule out the presence of bladder cancer.

All cancer cells – in every cancer type – are continually dividing (replicating) so contain MCM5.

But healthy cells which will normally line the bladder, and are therefore in contact with the urine, do not contain MCM5.

For example, when a tumour is present in the bladder, cancer cells are shed into the urine which means the MCM5 biomarker will be present and can be detected by Arquer  technology.