MCM Technology

MCM5 Proteins are excellent cancer biomarkers because:

  • They are robustly expressed in dividing cells and those preparing to divide
  • MCM proteins are not expressed in fully differentiated cells
  • When a mass of replicating cells, such as a bladder tumour, is present MCM positive cells are shed into the body fluids
  • MCM positive cells are not usually present in body fluids in the absence of cancer or epithelial damage
  • The MCM technology is applicable to a number of cancer types and there is a well-defined requirement for screening tests in number of cancer types for which the MCM technology could offer a clinically relevant test.

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